(2S,3R,4E)-2-Azido-3-(tert-butyldimethylsilyl)-erythro-sphingosine, Protein kinase C inhibitor (ab144921)
Key features and details
- Selective inhibitor of protein kinase C (PKC) activity and phorbol dibutyrate binding in vitro in human platelets.
- CAS Number: 114299-64-8
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(2S,3R,4E)-2-Azido-3-(tert-butyldimethylsilyl)-erythro-sphingosine, Protein kinase C inhibitor -
Description
Selective inhibitor of protein kinase C (PKC) activity and phorbol dibutyrate binding in vitro in human platelets. -
Alternative names
- (2S,3R,4E)-2-Azido-3-(tertbutyldimethylsilyl)-4-octadecene-3-ol
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Biological description
Derivative of Sphingosine. Selective inhibitor of protein kinase C (PKC) activity and phorbol dibutyrate binding in vitro in human platelets. Does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes.
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CAS Number
114299-64-8 -
Chemical structure
Properties
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Chemical name
(2S,3R,4E)-2-Azido-3-(tert-butyldimethylsilyl)-4-octadecene-3-ol -
Molecular weight
439.75 -
Molecular formula
C24H49N3O2Si -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic