2-Furoyl-LIGRLO-amide (2Fly), PAR2 agonist (ab120800)
Key features and details
- Potent and selective PAR2 agonist
- CAS Number: 729589-58-6
- Purity: > 95%
- Soluble in water to 1 mg/ml
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-Furoyl-LIGRLO-amide (2Fly), PAR2 agonist -
Description
Potent and selective PAR2 agonist -
Alternative names
- 2Fly
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Biological description
Potent and selective PAR2 receptor agonist (EC50 = 340 nM). Induces arterial contraction. Facilitates capsaicin evoked nociception. Around 100 times more potent than SLIGR-NH2 (ab120176). -
Purity
> 95% -
CAS Number
729589-58-6 -
Chemical structure
Properties
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Molecular weight
777.96 -
Molecular formula
C36H63N11O8 -
Sequence
LIGRLX (Modifications: N-terminal 2-Furoyl; C-terminal amide; X-6 = Orn) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 1 mg/ml -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
