Zerumbone, NF-kappaB inhibitor (ab142474)
Key features and details
- Potent NF-κB inhibitor. Anticancer agent.
- CAS Number: 471-05-6
- Purity: > 96%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Zingiber officinale
Overview
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Product name
Zerumbone, NF-kappaB inhibitor -
Description
Potent NF-κB inhibitor. Anticancer agent. -
Biological description
Potent NF-κB inhibitor. Anticancer agent. Induces cytochrome c dependent caspase activation and mitochondrial permeabilisation in cancer cells. Induces apoptosis and shows anti-inflammatory and antitumor effects in vivo. Orally active. -
Purity
> 96% -
CAS Number
471-05-6 -
Chemical structure
Properties
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Chemical name
(2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trien-1-one -
Molecular weight
218.33 -
Molecular formula
C15H22O -
PubChem identifier
5470187 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CCC(C=CC(=O)C(=CCC1)C)(C)C -
Source
Zingiber officinale
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Research areas
