VAS 2870, NADPH oxidase inhibitor (ab145209)
Key features and details
- NADPH oxidase inhibitor
- CAS Number: 722456-31-7
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
VAS 2870, NADPH oxidase inhibitor -
Description
NADPH oxidase inhibitor -
Biological description
NADPH oxidase inhibitor. Blocks PDGF-mediated NADPH activation and ROS production. Inhibits PMS-induced oxidative burst (IC50 = 2 μM, HeLa cells). Shows anti-ischemic effects ex vivo. -
Purity
> 98% -
CAS Number
722456-31-7 -
Chemical structure
Properties
-
Chemical name
3-Benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo(4,5-d)pyrimidine -
Molecular weight
360.40 -
Molecular formula
C18H12N6OS -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
c1cccc2oc(nc12)Sc5ncnc4c5nnn4Cc3ccccc3 -
Source
Synthetic
-
Research areas