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UPF 1069, PARP2 inhibitor (ab144831)

Key features and details

  • Selective PARP2 inhibitor
  • CAS Number: 1048371-03-4
  • Purity: > 99%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    UPF 1069, PARP2 inhibitor
  • Description

    Selective PARP2 inhibitor
  • Biological description

    Selective PARP2 inhibitor (IC50 = 0.3 μM). Induces apoptosis. Shows neurprotective and anti-ischemic effects in vivo.
  • Purity

    > 99%
  • CAS Number

    1048371-03-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-(2-Oxo-2-phenylethoxy)-1(2H)-isoquinolinone
  • Molecular weight

    279.29
  • Molecular formula

    C17H13NO3
  • PubChem identifier

    25015515
  • Storage instructions

    Store at room temperature.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C(C=C1)C(=O)COC2=CC=CC3=C2C=CNC3=O
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Nucleus
    • PARP
    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • ADP-ribosylation
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • Base Excision Repair
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • DNA Damage Response
    • DNA Damage Recognition
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Polymerase & Transcriptase
    • PARP
    • Inhibitors
    • Cancer
    • Cell Death
    • Apoptosis
    • Nucleus
    • PARP

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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