UNC0638, G9 and GLP histone methyltransferase inhibitor (ab142157)
Key features and details
- Potent, selective and reversible G9 and GLP histone methyltransferase inhibitor
- CAS Number: 1255580-76-7
- Purity: > 98%
- Soluble in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
UNC0638, G9 and GLP histone methyltransferase inhibitor -
Description
Potent, selective and reversible G9 and GLP histone methyltransferase inhibitor -
Biological description
Potent, selective and reversible G9 and GLP histone methyl transferase inhibitor (IC50 values are 15 and 19 nM respectively). Maintains HSC multipotency in vitro. Cell-permeable. -
Purity
> 98% -
CAS Number
1255580-76-7 -
Chemical structure
Properties
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Chemical name
2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine -
Molecular weight
509.72 -
Molecular formula
C30H47N5O2 -
PubChem identifier
46224516 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5 -
Source
Synthetic
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Research areas
