Tyrphostin AG 957, p210 tyrosine kinase inhibitor (ab141172)
Key features and details
- Potent, selective p210 tyrosine kinase inhibitor
- CAS Number: 140674-76-6
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tyrphostin AG 957, p210 tyrosine kinase inhibitor -
Description
Potent, selective p210 tyrosine kinase inhibitor -
Biological description
Potent, selective p210 tyrosine kinase inhibitor (IC50 values are 1 and 7.1 μM at p210bcr-abl and p140c-abl respectively). Able to induce apoptosis and growth arrest by affecting the phosphorylation state of PI3K/Akt.
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Purity
> 99% -
CAS Number
140674-76-6 -
Chemical structure
Properties
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Chemical name
4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid methyl ester -
Molecular weight
273.29 -
Molecular formula
C15H15NO4 -
PubChem identifier
2064 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Oc2ccc(O)cc2CNc1ccc(cc1)C(=O)OC -
Source
Synthetic
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Research areas
