Tyrphostin 47, EGFR tyrosine kinase inhibitor (ab141558)
Key features and details
- EGFR tyrosine kinase inhibitor
- CAS Number: 122520-86-9
- Purity: > 99%
- Soluble in DMSO to 75 mM and in ethanol to 75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tyrphostin 47, EGFR tyrosine kinase inhibitor -
Description
EGFR tyrosine kinase inhibitor -
Biological description
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50 = 2.4 μM). Also inhibits platelet-derived growth factor (PDGF) receptor tyrosine kinase. -
Purity
> 99% -
CAS Number
122520-86-9 -
Chemical structure
Properties
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Chemical name
2-Cyano-3-(3,4-dihydroxyphenyl)-2E-propenethioamide -
Molecular weight
220.20 -
Molecular formula
C10H8N2O2S -
PubChem identifier
5328803 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 75 mM and in ethanol to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Oc1ccc(\C=C(/C#N)C(N)=S)cc1O -
Source
Synthetic
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Research areas
