Tetrabenazine, VMAT2 inhibitor (ab146166)
Key features and details
- Potent, reversible VMAT2 inhibitor
- CAS Number: 58-46-8
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tetrabenazine, VMAT2 inhibitor -
Description
Potent, reversible VMAT2 inhibitor -
Biological description
Potent, reversible VMAT2 inhibitor (IC50 = 3.2 nM, Ki = 100 nM). Depletes monoamines stores and decreases uptake into synaptic vesicles. Shows antihyperkinetic effects in vivo. Orally active. -
CAS Number
58-46-8 -
Chemical structure
Properties
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Molecular weight
317.42 -
Molecular formula
C19H27NO3 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)CC2CN3CCc1cc(OC)c(OC)cc1C3CC2=O -
Source
Synthetic
