TAK 715, p38 MAPK inhibitor (ab120989)
Key features and details
- Potent p38 MAPK inhibitor
- CAS Number: 303162-79-0
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TAK 715, p38 MAPK inhibitor -
Description
Potent p38 MAPK inhibitor -
Biological description
Potent p38 MAPK inhibitor (IC50 = 7.1 nM at p38 MAPKα). Additionally inhibits Wnt-3a stimulated β-catenin signaling and shows cross-reactivity with casein kinase Iδ and ε. Antirheumatic. Active in vivo.
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Purity
> 99% -
CAS Number
303162-79-0 -
Chemical structure
Properties
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Chemical name
N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide -
Molecular weight
399.51 -
Molecular formula
C24H21N3OS -
PubChem identifier
9952773 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCc2nc(c1cc(C)ccc1)c(s2)c4ccnc(NC(=O)c3ccccc3)c4 -
Source
Synthetic
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Research areas