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SR 59230A hydrochloride, beta3 adrenoceptor antagonist (ab141135)

Price and availability

469 056 ₸

Availability

Order now and get it on Friday March 05, 2021

Key features and details

  • Potent, selective β3 adrenoceptor antagonist
  • CAS Number: 1135278-41-9
  • Purity: > 99%
  • Soluble in water to 10 mM and DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    SR 59230A hydrochloride, beta3 adrenoceptor antagonist
  • Description

    Potent, selective β3 adrenoceptor antagonist
  • Biological description

    Potent, selective β3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for β3, β1 and β2, respectively). Orally active in vivo.

  • Purity

    > 99%
  • CAS Number

    1135278-41-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-1-(2-Ethylphenoxy)-3-[[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]-2-propanol hydrochloride
  • Molecular weight

    361.91
  • Molecular formula

    C21H27NO2.HCl
  • PubChem identifier

    24978529
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 10 mM and DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    With gentle heating this product rapidly dissolves in water to make a 100mM solution, however the product will quickly come out of solution on cooling. We therefore recommend making 100mM solutions in DMSO unless they are to be used immediately.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.CCc3ccccc3OC[C@@H](O)N[C@H]2CCCc1ccccc12
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Adrenergic Receptors
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Adrenoceptors
    • β
    • β3
    • Antagonist

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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