Sp-5,6-Dichloro-cBIMPS, cAMP-dependent protein kinase activator (ab145202)
Key features and details
- Cell-permeable, potent, selective activator of cAMP-dependent protein kinase
- CAS Number: 120912-54-1
- Purity: > 98%
- Soluble in DMSO to 100 mM and in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Sp-5,6-Dichloro-cBIMPS, cAMP-dependent protein kinase activator -
Description
Cell-permeable, potent, selective activator of cAMP-dependent protein kinase -
Alternative names
- Sp-5,6-DCl-cBiMPS
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Biological description
cAMP analog. Cell-permeable, potent activator of cAMP-dependent protein kinase (PKA; Ka = 30 nM); Selective for PKA over cGMP-dependent protein kinase (PKG; Ka = 10 µM). Not significantly hydrolyzed by type I, II or III phosphodiesterases.
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Purity
> 98% -
CAS Number
120912-54-1 -
Chemical structure
Properties
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Molecular weight
419.20 -
Molecular formula
C12H10NaN2O5PSCl2 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in water to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
