SCH 23390 hydrochloride, D1-like dopamine receptor antagonist (ab120597)
Key features and details
- Selective D1-like dopamine receptor antagonist
- CAS Number: 125941-87-9
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SCH 23390 hydrochloride, D1-like dopamine receptor antagonist -
Description
Selective D1-like dopamine receptor antagonist -
Biological description
Selective D1-like dopamine receptor antagonist. Ki values are 0.2 (D1), 0.3 (D5), 1100 (D2), 800 (D3) and 3000 nM (D4). Some activity at 5-HT receptors (Ki values are 6.3 and 14.8 nM for 5-HT1C and 5-HT2C, respectively). Antipsychotic properties. Centrally active following subcutaneous administration.
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Purity
> 99% -
CAS Number
125941-87-9 -
Chemical structure
Properties
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Chemical name
(R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride -
Molecular weight
324.25 -
Molecular formula
C17H18ClNO.HCl -
PubChem identifier
11957535 -
Storage instructions
Store at +4°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1CCC2=CC(=C(C=C2[C@H](C1)C3=CC=CC=C3)O)Cl.Cl -
Source
Synthetic
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Research areas
