SB431542, ALK inhibitor (ab120163)
Key features and details
- ALK inhibitor
- CAS Number: 301836-41-9
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SB431542, ALK inhibitor -
Description
ALK inhibitor -
Biological description
Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC50 = 94 nM), and 7. 3D Growth matrix component; also component of brain and blood vessel organoid differentiation media.
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Purity
> 99% -
CAS Number
301836-41-9 -
Chemical structure
Properties
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Chemical name
4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]benzamide -
Molecular weight
384.39 -
Molecular formula
C22H16N4O3 -
PubChem identifier
4521392 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NC(=O)c1ccc(cc1)c3nc(c2ccccn2)c(n3)c4ccc5OCOc5c4 -
Source
Synthetic
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Research areas
