Rosiglitazone potassium salt, PPARgamma agonist (ab145865)
Key features and details
- Potent, selective PPARγ agonist. Water soluble.
- CAS Number: 316371-84-3
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rosiglitazone potassium salt, PPARgamma agonist -
Description
Potent, selective PPARγ agonist. Water soluble. -
Biological description
Potent, selective PPARγ agonist (Kd = 43 nM, PPARγ ligand binding domain). Activates PPARγ expression (EC50 = 1 μM). Shows antidiabetic and hypoglycemic effects in vivo. Orally active. Water soluble.
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Purity
> 99% -
CAS Number
316371-84-3 -
Chemical structure
Properties
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Chemical name
5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione potassium salt -
Molecular weight
395.52 -
Molecular formula
C18H18KN3O3S -
PubChem identifier
11463585 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(CCOC1=CC=C(C=C1)CC2C(=O)[N-]C(=O)S2)C3=CC=CC=N3.[K+] -
Source
Synthetic
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Research areas
