Rimonabant, cannabinoid CB1 receptor antagonist/inverse agonist (ab144582)
Key features and details
- Potent and selective cannabinoid CB1 receptor antagonist/inverse agonist
- CAS Number: 168273-06-1
- Purity: > 98%
- Soluble in DMSO to 25 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Rimonabant, cannabinoid CB1 receptor antagonist/inverse agonist -
Description
Potent and selective cannabinoid CB1 receptor antagonist/inverse agonist -
Biological description
Potent and selective cannabinoid CB1 receptor antagonist/inverse agonist (Ki = 2 nM). Shows anoretic, antiobesogenic and central psychoactive effects in vivo. Blood-brain barrier permeable. Orally active. -
Purity
> 98% -
CAS Number
168273-06-1 -
Chemical structure
Properties
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Chemical name
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-yl-1H-pyrazole-3-carboxamide -
Molecular weight
463.80 -
Molecular formula
C22H21Cl3N4O -
PubChem identifier
104850 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Cl -
Source
Synthetic
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Research areas
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
