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Immunology Innate Immunity Chemokines Alpha Chemokines (CXC)

Recombinant mouse CXCL5 protein (Active) (ab243271)

Recombinant mouse CXCL5 protein (Active) (ab243271)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, HPLC, SDS-PAGE

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Preparation and Storage

  • Alternative names

    • C-X-C motif chemokine 5
    • Cxcl5
    • CXCL5_MOUSE
    • Cytokine LIX
    • GCP-2
    • GCP-2(9-78)
    • GCP2
    • Scyb5
    • Small-inducible cytokine B5
    see all
  • Function

    May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in neutrophil activation.
  • Sequence similarities

    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications

    GCP-2(1-78) and GCP-2(9-78) are produced by proteolytic cleavage after secretion from fibroblasts and epithelial cells. GCP-2(9-78) is the most prominent form. A number of additional N-terminal (processed between pos. 41 and 48) and C-terminal (processed between pos. 118 and 132) processed forms have been identified, probably also representing intermediate states.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P50228 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant mouse CXCL5 protein (Active) (ab243271)
    SDS-PAGE - Recombinant mouse CXCL5 protein (Active) (ab243271)
    SDS Page analysis of CXCL5 with ab243271.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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