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Immunology Adaptive Immunity T Cells CD

Recombinant mouse CD200 / OX2 protein (ab214615)

Key features and details

  • Expression system: CHO cells
  • Purity: >= 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

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Description

  • Product name

    Recombinant mouse CD200 / OX2 protein
    See all CD200 / OX2 proteins and peptides
  • Biological activity

    Shows the biological function of the CD200 / OX2 moiety and exerts a prolonged circulating halflife caused by the modified Fc domain.

  • Purity

    >= 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    CHO cells
  • Accession

    O54901
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      QVEVVTQDERKALHTTASLRCSLKTSQEPLIVTWQKKKAVSPENMVTYSK THGVVIQPAYKDRINVTELGLWNSSITFWNTTLEDEGCYMCLFNTFGSQK VSGTACLTLYVQPIVHLHYNYFEDHLNITCSATARPAPAISWKGTGTGIE NSTESHFHSNGTTSVTSILRVKDPKTQVGKEVICQVLYLGNVIDYKQSLD KGFWFS
    • Amino acids

      31 to 236
    • Additional sequence information

      The extracellular domain of mouse CD200 / OX2 (aa 31-236) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.
  • Specifications

    Our Abpromise guarantee covers the use of ab214615 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      Functional Studies

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Stable for 12 months at -20°C.

      Constituent: 99% PBS

      Lyophilized from 0.2 µm filtered solution.

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Reconstitute at 100 µg/mL in sterile PBS. Working aliquots are stable for up to 3 months when stored at -20°C.

    General Info

    • Alternative names

      • Antigen identified by monoclonal antibody MRC OX 2
      • CD200
      • CD200 antigen
      • CD200 molecule
      • MOX1
      • MOX2
      • MRC
      • MRC OX 2 antigen
      • My033
      • OX 2
      • OX 2 membrane glycoprotein precursor
      • OX-2 membrane glycoprotein
      • OX2G
      • OX2G_HUMAN
      see all
    • Function

      Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
    • Sequence similarities

      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession P41217 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab214615? Please let us know so that we can cite the reference in this datasheet.

    ab214615 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Antigen identified by monoclonal antibody MRC OX 2
    • CD200
    • CD200 antigen

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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