Recombinant Lysostaphin protein (ab70102)
Key features and details
- Expression system: Escherichia coli
- Active: Yes
- Suitable for: HPLC, Functional Studies
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Product name
Recombinant Lysostaphin protein -
Biological activity
Specific activity: 3,542 units/mg.
Assessed by the decrease in turbidity of a suspension of heat-killed Staphylococcus aureus at pH-8, 30°C. Lysostaphin is a zinc enzyme therefore EDTA is an inhibitory factor.
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Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Staphylococcus simulans -
Sequence
AATHEHSAQW LNNYKKGYGY GPYPLGINGG MHYGVDFFMN IGTPVKAISS GKIVEAGWSN YGGGNQIGLI ENDGVHRQWY MHLSKYNVKV GDYVKAGQII GWSGSTGYST APHLHFQRMV NSFSNSTAQD PMPFLKSAGY GKAGGTVTPT PNTGWKTNKY GTLYKSESAS FTPNTDIITR TTGPFRSMPQ SGVLKAGQTI HYDEVMKQDG HVWVGYTGNS GQRIYLPVRT WNKSTNTLGV LWGTIK -
Predicted molecular weight
27 kDa -
Amino acids
248 to 493 -
Additional sequence information
Full length mature protein, without the signal peptide or the propeptide.
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Description
Recombinant Lysostaphin protein (Active)
Preparation and Storage
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Alternative names
- Glycyl glycine endopeptidase
- lss
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Relevance
Lysostaphin is a Staphylococcus simulans metalloendopeptidase. It is an endopeptidase specific for the cell wall peptidoglycan of staphylococci and is an extremely potent anti-staphylococcal agent. Lysostaphin lyses staphylococcal cells by hydrolysing the -Gly-|-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans. -
Cellular localization
Secreted
