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Epigenetics and Nuclear Signaling Transcription Domain Families Zinc Finger

Recombinant Human ZIK1 protein (ab172813)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: T7 tag N-Terminus
  • Suitable for: HPLC, SDS-PAGE

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Description

  • Product name

    Recombinant Human ZIK1 protein
  • Purity

    > 95 % SDS-PAGE.
    Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    Q3SY52-3
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MASMTGGQQM GRGSMAAAAL RAPTQVTVSP ETHMDLTKGC VTFEDIAIYF SQDEWGLLDE AQRLL YLEV MLENFALVAS LGCGHGTEDE ETPSDQNVSV GVSQSKAGSS TQKTQSCEMC VPVLKDILHL A DLPGQKPY LVGECTNHHQ HQKHHSAKKS LKRDMDRASY VKCCLFCMSL KPFRKWEVGK DLPAMLR LL RSLVFPGGKK PGTITECGED IRSQKSHYKS GECGKASRHK HTPVYHPRVY TGKKLYECSK CGK AFRGKY SLVQHQRVHT GERPWECNEC GKFFSQTSHL NDHRRIHTGE RPYECSECGK LFRQNSSLV DHQKIHTGAR PYECSQCGKS FSQKATLVKH QRVHTGERPY KCGECGNSFS QSAILNQHRR IHTGA KPYE CGQC
    • Predicted molecular weight

      45 kDa including tags
    • Amino acids

      1 to 384
    • Tags

      T7 tag N-Terminus
  • Associated products

    • Related Products

      • Anti-T7 tag® antibody (ab9115)
      • Anti-T7 tag® antibody (ab9138)

    Specifications

    Our Abpromise guarantee covers the use of ab172813 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituent: 0.24% Tris

      Supplied as a 0.2 µM filtered solution

    General Info

    • Alternative names

      • ZIK1
      • ZIK1_HUMAN
      • Zinc finger protein 762
      • Zinc finger protein interacting with K protein 1
      • Zinc finger protein interacting with ribonucleoprotein K
      see all
    • Function

      May be a transcriptional repressor.
    • Tissue specificity

      Expressed at high levels in gastric glands, and at low levels in colon and small intestine. Silenced through promoter methylation in gastric glands with intestinal metaplasia.
    • Sequence similarities

      Belongs to the krueppel C2H2-type zinc-finger protein family.
      Contains 9 C2H2-type zinc fingers.
      Contains 1 KRAB domain.
    • Cellular localization

      Nucleus.
    • Target information above from: UniProt accession Q3SY52 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab172813? Please let us know so that we can cite the reference in this datasheet.

    ab172813 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituent: 0.24% Tris

      Supplied as a 0.2 µM filtered solution

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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