Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human YKL-40/CHI3L1 protein (ab151938)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C.

    pH: 7.40
    Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at

    General Info

    • Alternative names

      • 39 kDa synovial protein
      • ASRT7
      • Cartilage glycoprotein 39
      • CGP-39
      • CGP39
      • CH3L1_HUMAN
      • CHI3L1
      • chitinase
      • chitinase 3 like 1
      • chitinase 3 like 1 (cartilage glycoprotein 39)
      • Chitinase 3 like protein 1 precursor
      • Chitinase-3-like protein 1
      • Chondrocyte protein YKL40
      • GP 39
      • GP-39
      • GP39
      • HC gp39
      • HCGP 3P
      • hCGP-39
      • HCgp39
      • YKL 40
      • YKL-40
      • YKL40
      • YYL 40
      see all

    • Function

      Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.

    • Tissue specificity

      Present in activated macrophages, articular chondrocytes, synovial cells as well as in liver. Undetectable in muscle tissues, lung, pancreas, mononuclear cells, or fibroblasts.

    • Involvement in disease

      A genetic variation in CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) [MIM:611960]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea, bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.

    • Sequence similarities

      Belongs to the glycosyl hydrolase 18 family.

    • Post-translational
      modifications

      Glycosylated.

    • Cellular localization

      Secreted > extracellular space.
    • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

References (0)

Publishing research using ab151938? Please let us know so that we can cite the reference in this datasheet.

ab151938 has not yet been referenced specifically in any publications.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Alternative products to Recombinant Human YKL-40/CHI3L1 protein (ab151938)

Get resources and offers direct to your inbox Sign up