Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human VRK3 protein (ab199586)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human VRK3 protein
    See all VRK3 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Supplied as a 0.2 µM filtered solution.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q8IV63-2

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MISFCPDCGKSIQAAFKFCPYCGNSLPVEEHVGSQTFVNPHVSSFQGSKR GLNSSFETSPKKVKWSSTVTSPRLSLFSDGDSSESEDTLSSSERSKGSGS RPPTPKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSLE ALPTGTVLTDKSGRQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKF SLKLDAKDGRLFNEQNFFQRAAKPLQVNKWKKLYSTPLLAIPTCMGFGVH QDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLHEN EYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGKHVAYVEGSRSPH EGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDI MKQKQKLPWDSFVDHHHHHH

    • Predicted molecular weight

      47 kDa including tags

    • Amino acids

      1 to 412

    • Tags

      His tag C-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab199586 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -20°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 0.87% Sodium chloride, 99% Phosphate Buffer

    General Info

    • Alternative names

      • Inactive serine/threonine-protein kinase VRK3
      • Serine/threonine protein kinase VRK3
      • Serine/threonine-protein pseudokinase VRK3
      • Vaccinia related kinase 3
      • Vaccinia-related kinase 3
      • Vrk3
      • VRK3_HUMAN
      see all

    • Function

      Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus.

    • Sequence similarities

      Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.
      Contains 1 protein kinase domain.

    • Cellular localization

      Nucleus.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab199586? Please let us know so that we can cite the reference in this datasheet.

ab199586 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -20°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.87% Sodium chloride, 99% Phosphate Buffer

Images

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