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Signal Transduction Metabolism Vitamins / Minerals

Recombinant Human VNN2 protein (His tag) (ab276424)

Recombinant Human VNN2 protein (His tag) (ab276424)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human VNN2 protein (His tag)
  • Purity

    > 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    O95498
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MVTSSFPISV AVFALITLQV GTQDSFIAAV YEHAVILPNK TETPVSQEDA LNLMNENIDI LETAIKQAAE QGARIIVTPE DALYGWKFTR ETVFPYLEDI PDPQVNWIPC QDPHRFGHTP VQARLSCLAK DNSIYVLANL GDKKPCNSRD STCPPNGYFQ YNTNVVYNTE GKLVARYHKY HLYSEPQFNV PEKPELVTFN TAFGRFGIFT CFDIFFYDPG VTLVKDFHVD TILFPTAWMN VLPLLTAIEF HSAWAMGMGV NLLVANTHHV SLNMTGSGIY APNGPKVYHY DMKTELGKLL LSEVDSHPLS SLAYPTAVNW NAYATTIKPF PVQKNTFRGF ISRDGFNFTE LFENAGNLTV CQKELCCHLS YRMLQKEENE VYVLGAFTGL HGRRRREYWQ VCTLLKCKTT NLTTCGRPVE TASTRFEMFS LSGTFGTEYV FPEVLLTEIH LSPGKFEVLK DGRLVNKNGS SGPILTVSLF GRWYTKDSLY SS
    • Predicted molecular weight

      55 kDa including tags
    • Molecular weight information

      The recombinant human VNN2 consists of 481 amino acids and predicts a molecular mass of 54.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhVNN2 is approximately 55-60 kDa due to glycosylation.
    • Amino acids

      1 to 492
    • Tags

      His tag C-Terminus
    • Additional sequence information

      Predicted N-terminus: Gln 23.
  • Specifications

    Our Abpromise guarantee covers the use of ab276424 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • FOAP-4
      • Glycosylphosphatidyl inositol-anchored protein GPI-80
      • GPI-80
      • OTTHUMP00000017228
      • OTTHUMP00000233789
      • OTTHUMP00000233791
      • pantetheinase
      • Protein FOAP-4
      • vanin 2
      • Vanin-2
      • Vannin 2
      • Vascular non-inflammatory molecule 2
      see all
    • Relevance

      This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene.
    • Cellular localization

      Cell Membrane; Lipid-anchor, GPI-anchor

Images

  • SDS-PAGE - Recombinant Human VNN2 protein (ab276424)
    SDS-PAGE - Recombinant Human VNN2 protein (ab276424)
    SDS-PAGE analysis of ab276424

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276424? Please let us know so that we can cite the reference in this datasheet.

    ab276424 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • FOAP-4
    • Glycosylphosphatidyl inositol-anchored protein GPI-80
    • GPI-80

    Images

    • SDS-PAGE - Recombinant Human VNN2 protein (ab276424)
      SDS-PAGE - Recombinant Human VNN2 protein (ab276424)
      SDS-PAGE analysis of ab276424

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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