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Signal Transduction Protein Trafficking ER Proteins

Recombinant Human TXNDC4 protein (ab185850)

Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant Human TXNDC4 protein
    See all TXNDC4 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    Assessed also by SEC-HPLC
  • Endotoxin level

  • Expression system

    Mammalian
  • Accession

    Q9BS26
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      EITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEF PNENQVVFARVDCDQ HSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPI QEIRDLAEITTLDRS KRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNI IYKPPGHSAPDMVYL GAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTE SLEIFQNEVARQLIS EKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVL IPGKLKQFVFDLHSG KLHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDVD HHHHHH
    • Predicted molecular weight

      44 kDa including tags
    • Amino acids

      30 to 402
    • Tags

      His tag C-Terminus
  • Associated products

    • Related Products

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)

    Specifications

    Our Abpromise guarantee covers the use of ab185850 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituents: 0.32% Tris HCl, 10% Glycerol

      Supplied as a 0.2 µM filtered solution

    General Info

    • Alternative names

      • Endoplasmic reticulum resident protein 44
      • Endoplasmic reticulum resident protein 44 kDa
      • Endoplasmic reticulum resident protein ERp44
      • ER protein 44
      • ERp44
      • ERP44_HUMAN
      • KIAA0573
      • PDIA10
      • Protein disulfide isomerase family A, member 10
      • Thioredoxin domain containing 4 (endoplasmic reticulum)
      • Thioredoxin domain containing protein 4
      • Thioredoxin domain-containing protein 4
      • UNQ532/PRO1075
      see all
    • Function

      Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
    • Sequence similarities

      Contains 1 thioredoxin domain.
    • Cellular localization

      Endoplasmic reticulum lumen.
    • Target information above from: UniProt accession Q9BS26 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab185850? Please let us know so that we can cite the reference in this datasheet.

    ab185850 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituents: 0.32% Tris HCl, 10% Glycerol

      Supplied as a 0.2 µM filtered solution

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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