Recombinant human TRAIL protein (Active) (ab256115)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Preparation and Storage
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Alternative names
- Apo 2 ligand
- APO 2L
- Apo-2 ligand
see all -
Function
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. -
Tissue specificity
Widespread; most predominant in spleen, lung and prostate. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant human TRAIL protein (Active) (ab256115)
SDS-PAGE analysis of ab256115 (1μg) under reducing (Lane 1) and non-reducing (Lane 2) conditions. ab256115 is predicted to have a MW of 19.5 kDa.
4-20% Tris-Glycine gel. Coomassie Blue staining