Recombinant human TRAIL protein (ab168898)
Key features and details
- Expression system: Escherichia coli
- Purity: >= 99% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Tags: His tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.40
Constituents: 0.02% DTT, 0.01% Tween, 0.48% HEPES, 1% Sucrose, 1.75% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
Images
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Apoptosis of TRAIL-sensitive cells. Concentration dependence of apoptosis induction in Jurkat and BJAB cells by ab168898 reveals high activity even at concentrations of 10-100 ng/ml.
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Specificity of ab168898-induced apoptosis. Concentration dependent blocking of apoptosis induction of BJAB cells using MAb to Human TRAIL reveals specificity of ab168898-mediated killing.
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Apoptosis of TRAIL-sensitive myeloid cell line ML-1.
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Flow cytometry analysis of the TRAIL-sensitive human leukemia cell line HL60 and of TRAIL-resistant K572 cells using ab168898.