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Signal Transduction Signaling Pathway Nuclear Signaling NFkB Pathway

Recombinant Human TNFRSF19L protein (ab191989)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: HPLC, SDS-PAGE

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Description

  • Product name

    Recombinant Human TNFRSF19L protein
    See all TNFRSF19L proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    determined by SEC-HPLC and reducing SDS-PAGE.
  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    Q969Z4
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      STTLWQCPPGEEPDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWR RLEAQVGMATRDTLCGDCWPGWFGPWGVPRVPCQPCSWAPLGTHGCDEWG RRARRGVEVAAGASSGGETRQPGNGTRAGGPEETAVDDIEGRMDEPKSCD KTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDP EVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKC KVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKG FYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGN VFSCSVMHEALHNHYTQKSLSLSPGK
    • Predicted molecular weight

      41 kDa including tags
    • Amino acids

      26 to 160
    • Additional sequence information

      Extracellular domain, fused with a FC tag at the C-terminus.
  • Specifications

    Our Abpromise guarantee covers the use of ab191989 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.2
      Constituents: 1.19% HEPES, 0.87% Sodium chloride, 10% Glycerol (glycerin, glycerine), 0.03% DTT

    General Info

    • Alternative names

      • Receptor expressed in lymphoid tissues
      • Relt
      • TNFRSF19L
      • TR19L_HUMAN
      • Tumor necrosis factor receptor superfamily member 19L
      see all
    • Function

      Mediates activation of NF-kappa-B. May play a role in T-cell activation.
    • Tissue specificity

      Highest levels are in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in brain, kidney and pancreas.
    • Sequence similarities

      Belongs to the RELT family.
      Contains 1 TNFR-Cys repeat.
    • Post-translational
      modifications

      Phosphorylated in vitro by OXSR1.
    • Cellular localization

      Cell membrane. Cytoplasm.
    • Target information above from: UniProt accession Q969Z4 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab191989? Please let us know so that we can cite the reference in this datasheet.

    ab191989 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Receptor expressed in lymphoid tissues
    • Relt
    • TNFRSF19L

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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