Recombinant human TNFRSF14/HVEM protein (Active) (ab271546)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Active: Yes
- Tags: Fc tag C-Terminus
- Suitable for: Functional Studies, SDS-PAGE
-
Product name
Recombinant human TNFRSF14/HVEM protein (Active)
See all TNFRSF14/HVEM proteins and peptides -
Biological activity
Active in a BTLA:TNFRSF14/HVEM binding assay.
-
Purity
>= 90 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
PALPSCKEDE YPVGSECCPK CSPGYRVKEA CGELTGTVCE PCPPGTYIAH LNGLSKCLQC QMCDPAMGLR ASRNCSRTEN AVCGCSPGHF CIVQDGDHCA ACRAYATSSP GQRVQKGGTE SQDTLCQNCP PGTFSPNGTL EECQHQTKCS WLVTKAGAGT SSSHWV -
Predicted molecular weight
44 kDa including tags -
Molecular weight information
Protein runs at higher than predicted MW on SDS-PAGE due to glycosylation. -
Amino acids
37 to 202 -
Tags
Fc tag C-Terminus -
Additional sequence information
Human IgG1 Fc. Genbank: NM_003820
-
Preparation and Storage
-
Alternative names
- HVEML
- ATAR
- CD270
see all -
Function
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. -
Tissue specificity
Widely expressed, with the highest expression in lung, spleen and thymus. -
Sequence similarities
Contains 3 TNFR-Cys repeats. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Membrane. - Information by UniProt
Images
-
Functional Studies - Recombinant human TNFRSF14/HVEM protein (Active) (ab271546)
Functional analysis of ab271546.
Active in a BTLA:TNFRSF14/HVEM binding assay.
-
SDS-PAGE - Recombinant Human TNFRSF14/HVEM protein (Tagged) (ab271546)SDS-PAGE analysis of ab271546.