Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human SPINK1/P12 protein (ab152041)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human SPINK1/P12 protein
    See all SPINK1/P12 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    ab152041 was determined to be >95% pure by SEC-HPLC and reducing SDS-PAGE. Supplied as a 0.2 µM filtered solution.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    P00995

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      DSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQTSILI QKSGPCVDHH HHHH

    • Predicted molecular weight

      7 kDa including tags

    • Amino acids

      24 to 79

    • Tags

      His tag C-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab152041 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid

    • Additional notes

       This product was previously labelled as SPINK1

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 6.00
      Constituents: 0.392% MES, 0.05% Brij, 0.02% Calcium chloride, 0.02% DTT, 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

    General Info

    • Alternative names

      • ISK1_HUMAN
      • Pancreatic secretory trypsin inhibitor
      • Pancreatic serine protease inhibitor Kazal
      • PCTT
      • PSTI
      • Serine protease inhibitor Kazal type 1
      • Serine protease inhibitor Kazal-type 1
      • Spink 3
      • SPINK1
      • Spink3
      • TaTI
      • TCP
      • Tumor associated trypsin inhibitor
      • Tumor-associated trypsin inhibitor
      see all

    • Function

      Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.
      In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.

    • Involvement in disease

      Pancreatitis, hereditary
      Tropical calcific pancreatitis

    • Sequence similarities

      Contains 1 Kazal-like domain.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab152041? Please let us know so that we can cite the reference in this datasheet.

ab152041 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 6.00
    Constituents: 0.392% MES, 0.05% Brij, 0.02% Calcium chloride, 0.02% DTT, 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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