Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human SENP2 protein (ab199592)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag N-Terminus
  • Suitable for: HPLC, SDS-PAGE

Description

  • Product name

    Recombinant Human SENP2 protein
    See all SENP2 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q9HC62

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGHHHHHHGSLQDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIK KTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQAPEDLDMEDNDIIE AHREQIGGDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQT LKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAV KRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRI CEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCK YADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL

    • Predicted molecular weight

      39 kDa including tags

    • Amino acids

      363 to 589

    • Tags

      His tag N-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab199592 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      HPLC

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 5% Glycerol (glycerin, glycerine), 1.19% HEPES

    General Info

    • Alternative names

      • Axam2
      • DKFZp762A2316
      • KIAA1331
      • Senp2
      • SENP2_HUMAN
      • Sentrin specific protease 2
      • Sentrin-specific protease 2
      • Sentrin/SUMO specific protease SENP2
      • Sentrin/SUMO-specific protease SENP2
      • SMT3 specific isopeptidase 2
      • SMT3-specific isopeptidase 2
      • Smt3ip2
      • SUMO1/sentrin/SMT3 specific peptidase 2
      see all

    • Function

      Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.

    • Sequence similarities

      Belongs to the peptidase C48 family.

    • Domain

      The N-terminus is necessary and sufficient for nuclear envelope targeting.

    • Post-translational
      modifications

      Polyubiquitinated; which leads to proteasomal degradation.

    • Cellular localization

      Nucleus > nuclear pore complex. Nucleus membrane. Cytoplasm. Shuttles between cytoplasm and nucleus.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab199592? Please let us know so that we can cite the reference in this datasheet.

ab199592 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 5% Glycerol (glycerin, glycerine), 1.19% HEPES

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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