Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human Semenogelin I protein (ab153783)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 4.50
    Constituents: 99% Sodium acetate, 0.88% Sodium chloride

  • Reconstitution
    Lyophilized from a 0.2 µM filtered solution. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at

    General Info

    • Alternative names

      • Alpha-Inhibin-31
      • Alpha-Inhibin-92
      • Cancer/testis antigen 103
      • CT103
      • dJ172H20.2
      • dJ172H20.2 (semenogelin I)
      • MGC14719
      • Semen coagulating protein
      • Semenogelin
      • Semenogelin I
      • SEMG
      • SEMG1
      • SEMG1_HUMAN
      • Seminal basic protein
      • seminal vesicle secretory protein 5
      • SgI
      • Svp-1
      • Svp5
      • SVPIIA
      • Svs2
      • SVS2P
      • Svs2p2
      • Svs5
      see all

    • Function

      Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA.
      Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.

    • Tissue specificity

      Seminal vesicle.

    • Sequence similarities

      Belongs to the semenogelin family.

    • Post-translational
      modifications

      Transglutaminase substrate.
      Rapidly cleaved after ejaculation by KLK3/PSA, resulting in liquefaction of the semen coagulum and the progressive release of motile spermatozoa.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

References (0)

Publishing research using ab153783? Please let us know so that we can cite the reference in this datasheet.

ab153783 has not yet been referenced specifically in any publications.

Images

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