Recombinant human SDF1 protein (ab229846)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, MS, SDS-PAGE, Functional Studies
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Product name
Recombinant human SDF1 protein
See all SDF1 proteins and peptides -
Biological activity
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Purity
> 98 % SDS-PAGE.
Expressed in E. coli then processed, refolded and purified to yield the native, secreted form of the mature chemokine. >98% pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
8 kDa -
Additional sequence information
(Expressed in E.coli). Secreted form.
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Preparation and Storage
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Applications
HPLC
Mass Spectrometry
SDS-PAGE
Functional Studies
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Mass spectrometry
MALDI-TOF -
Form
Lyophilized -
Additional notes
C-X-C motif chemokine 12 alpha (CXCL12-alpha) is a 68 amino acid Cys-X-Cys chemokine that is involved in diverse cellular functions including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. CXCL12-alpha is also known as stromal cell-derived factor 1 alpha (SDF-1-alpha) and is processed from the 72 amino acid CXCL12/SDF-1 by proteolytic cleavage after secretion. The C-terminal processing to isoform CXCL12-alpha is reduced by binding to heparin and cell surface proteoglycans.
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Concentration information loading...
Images
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Functional Studies - Recombinant human SDF1 protein (ab229846)
ab229846 activity verified by intracellular calcium flux using THP1 cells.
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Mass Spectrometry - Recombinant human SDF1 protein (ab229846)