Recombinant Human Scn2b protein (His tag) (ab276596)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human Scn2b protein (His tag) -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MHRDAWLPRP AFSLTGLSLF FSLVPPGRSM EVTVPATLNV LNGSDARLPC TFNSCYTVNH KQFSLNWTYQ ECNNCSEEMF LQFRMKIINL KLERFQDRVE FSGNPSKYDV SVMLRNVQPE DEGIYNCYIM NPPDRHRGHG KIHLQVLMEE PPERDSTVA -
Predicted molecular weight
17 kDa including tags -
Molecular weight information
The recombinant human SCN2B consists of 141 amino acids and predicts a molecular mass of 16.6 KDa. It migrates as an approximately 24-33 KDa band in SDS-PAGE under reducing conditions. -
Amino acids
1 to 159 -
Tags
His tag C-Terminus -
Additional sequence information
Predicted N-terminus: Met 30.
Specifications
Our Abpromise guarantee covers the use of ab276596 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.4
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- Neuronal voltage gated sodium channel beta 2 subunit
- Scn 2b
- Scn2b
see all -
Function
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. -
Tissue specificity
Brain specific. -
Sequence similarities
Belongs to the sodium channel auxiliary subunit SCN2B (TC 8.A.17) family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human Scn2b protein (ab276596)SDS-PAGE analysis of ab276596
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276596 has not yet been referenced specifically in any publications.
Preparation and Storage
- Neuronal voltage gated sodium channel beta 2 subunit
- Scn 2b
- Scn2b
Images
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SDS-PAGE - Recombinant Human Scn2b protein (ab276596)SDS-PAGE analysis of ab276596