Recombinant Human ROR1 protein (Tagged) (ab269987)
Key features and details
- Expression system: HEK 293 cells
- Tags: Avi tag C-Terminus, Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human ROR1 protein (Tagged)
See all ROR1 proteins and peptides -
Purity
>90% by SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
ARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQ TAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDT TDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPY RGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFA IPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMI LMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRG TVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPW CFTLDENFKSDLCDIPACDSKDSKEKNKME -
Predicted molecular weight
71 kDa including tags -
Amino acids
24 to 403 -
Tags
Avi tag C-Terminus , Fc tag C-Terminus -
Additional sequence information
C-terminal Avi-TagTM fused to the Fc portion of Human IgG1. NM_005012
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Preparation and Storage
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Alternative names
- dJ537F10.1
- Inactive tyrosine protein kinase transmembrane receptor ROR1
- MGC99659
see all -
Function
Tyrosine-protein kinase receptor whose role is not yet clear. -
Tissue specificity
Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
Contains 1 FZ (frizzled) domain.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 kringle domain.
Contains 1 protein kinase domain. -
Developmental stage
Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. -
Cellular localization
Membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human ROR1 protein (Tagged) (ab269987)
SDS-Page analysis of 4 µg ab269987 (Lane 1).
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Size Exclusion Chromatography - Recombinant Human ROR1 protein (Tagged) (ab269987)Aggregation analysis of ab269987.
