Recombinant Human ROR1 protein (ab245799)
Key features and details
- Expression system: CHO cells
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE, HPLC
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Product name
Recombinant Human ROR1 protein
See all ROR1 proteins and peptides -
Purity
> 95 % SDS-PAGE.
>95 % by HPLC analysis. -
Expression system
CHO cells -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
QETELSVSAELVPTSSWNISSELNKDSYLTLDEPMNNITTSLGQTAELHC KVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYF QCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACA RFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCH YAFPYCDETSSVPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKL PNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTK SGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDE NFKSDLCDIPACDSKDSKEKNKMEILY -
Predicted molecular weight
42 kDa -
Amino acids
30 to 406 -
Additional sequence information
Extracellular domain.
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Preparation and Storage
-
Alternative names
- dJ537F10.1
- Inactive tyrosine protein kinase transmembrane receptor ROR1
- MGC99659
see all -
Function
Tyrosine-protein kinase receptor whose role is not yet clear. -
Tissue specificity
Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
Contains 1 FZ (frizzled) domain.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 kringle domain.
Contains 1 protein kinase domain. -
Developmental stage
Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. -
Cellular localization
Membrane. - Information by UniProt
