Recombinant Human Properdin/PFC protein (ab114924)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, SDS-PAGE, ELISA
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Product name
Recombinant Human Properdin/PFC protein
See all Properdin/PFC proteins and peptides -
Expression system
Wheat germ -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
PHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGP WGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPC PVDGEWDSWGEWSPCIRRNMKS -
Predicted molecular weight
39 kDa including tags -
Amino acids
213 to 334
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Preparation and Storage
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Alternative names
- BFD
- CFP
- Complement factor P
see all -
Function
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. -
Involvement in disease
Defects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III). -
Sequence similarities
Contains 6 TSP type-1 domains. -
Cellular localization
Secreted. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human Properdin/PFC protein (ab114924)12.5% SDS-PAGE showing ab114924 at approximately 39.05kDa.
Stained with Coomassie Blue.
