Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human Junctional Adhesion Molecule 2/JAM-B protein (ab192298)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human Junctional Adhesion Molecule 2/JAM-B protein
    See all Junctional Adhesion Molecule 2/JAM-B proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    Purity greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    P57087

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      FSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQT LQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTL EVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLEN PRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK RMQVDDLNVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPK DTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNS TYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQV YTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVL DSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG

    • Predicted molecular weight

      50 kDa including tags

    • Amino acids

      29 to 236

    • Additional sequence information

      Fused with a FC tag at the C-terminus.

    • Specifications

    Our Abpromise guarantee covers the use of ab192298 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized

    • Additional notes

      Previously labelled as Junctional Adhesion Molecule 2.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

      Lyophilized from a 0.2 µM filtered solution.

    General Info

    • Alternative names

      • C21orf43
      • CD 322
      • CD322
      • CD322 antigen
      • JAM 2
      • JAM B
      • JAM IT/VE JAM
      • JAM, vascular endothelial
      • JAM-2
      • JAM-B
      • JAM2
      • JAM2_HUMAN
      • JAMB
      • Jcam2
      • Junction adhesion molecule 2
      • Junction adhesion molecule B
      • Junctional adhesion molecule 2
      • Junctional adhesion molecule B
      • PRO 245
      • PRO245
      • Vascular endothelial junction associated molecule
      • Vascular endothelial junction-associated molecule
      • VE JAM
      • VE-JAM
      • VEJAM
      see all

    • Function

      May play a role in the processes of lymphocyte homing to secondary lymphoid organs.

    • Tissue specificity

      Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells.

    • Sequence similarities

      Belongs to the immunoglobulin superfamily.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Cellular localization

      Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab192298? Please let us know so that we can cite the reference in this datasheet.

ab192298 has not yet been referenced specifically in any publications.

Preparation and Storage

  • C21orf43
  • CD 322
  • CD322

Images

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