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Neuroscience Neurotransmission Intracellular Signaling Kinases

Recombinant Human JAK1 (mutated E966V) protein (Tagged) (ab268687)

Recombinant Human JAK1 (mutated E966V) protein (Tagged) (ab268687)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Insect cells
  • Purity: > 85% SDS-PAGE
  • Tags: GST tag N-Terminus
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant Human JAK1 (mutated E966V) protein (Tagged)
    See all JAK1 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Insect cells
  • Accession

    P23458
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      NGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQ VQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNIS FMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGE HLGRGTRTHIYSGTLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFE AASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLT TPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKL SDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEIC YNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPF FRAIMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFG KVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENI VKYKGICTEDGGNGIKLIMEFLPSGSLKVYLPKNKNKINLKQQLKYAVQI CKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTV KDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMAL FLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPS NRTSFQNLIEGFEALLK
    • Predicted molecular weight

      133 kDa including tags
    • Actual molecular weight

      105 kDa including tags
    • Amino acids

      438 to 1154
    • Modifications

      mutated E966V
    • Tags

      GST tag N-Terminus
    • Additional sequence information

      GenBank: NM_002227

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.5
    Constituents: 0.79% Tris HCl, 0.87% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine)

Images

  • SDS-PAGE - Recombinant Human JAK1 (mutated E966V) protein (Tagged) (ab268687)
    SDS-PAGE - Recombinant Human JAK1 (mutated E966V) protein (Tagged) (ab268687)

    SDS-PAGE analysis of ab268687.

  • Functional Studies - Recombinant Human JAK1 (mutated E966V) protein (Tagged) (ab268687)
    Functional Studies - Recombinant Human JAK1 (mutated E966V) protein (Tagged) (ab268687)

    ab268687 displayed no significant activity in a peptide kinase assay using IRS-1 (Y608) as substrate.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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