Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human INPP5A protein (ab199597)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human INPP5A protein

  • Purity

    > 95 % SDS-PAGE.
    Determined by SEC-HPLC and reducing SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q14642

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMA LHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEH FTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEK FPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPS VYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKA TMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGT ALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDR ILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGK PHAHVHKCCVDHHHHHH

    • Predicted molecular weight

      49 kDa including tags

    • Amino acids

      1 to 410

    • Tags

      His tag C-Terminus

    • Additional sequence information

      This product is for the mature full length protein. The propeptide is not included.

    • Specifications

    Our Abpromise guarantee covers the use of ab199597 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 0.87% Sodium chloride, 99% Phosphate Buffer

      Supplied as a 0.2 µm filtered solution

    General Info

    • Alternative names

      • 4
      • 43 kDa inositol polyphosphate 5-phophatase
      • 5-trisphosphate 5-phosphatase
      • 5PTase
      • CTCL tumor antigen HD-CL-02
      • DKFZp434A1721
      • I5P1
      • I5P1_HUMAN
      • Inositol polyphosphate 5 phosphatase
      • inositol polyphosphate-5-phosphatase A
      • inositol trisphosphate-5-phosphatase
      • INPP5A
      • INPP5A inositol polyphosphate-5-phosphatase
      • InsP3 5-phosphatase
      • MGC116947
      • MGC116949
      • Type I inositol-1
      • type I inositol-1,4,5-trisphosphate 5-phophatase
      see all

    • Function

      Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.

    • Tissue specificity

      Brain; high level in Purkinje cells.

    • Sequence similarities

      Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type I family.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab199597? Please let us know so that we can cite the reference in this datasheet.

ab199597 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.87% Sodium chloride, 99% Phosphate Buffer

    Supplied as a 0.2 µm filtered solution

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