Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human IL-28A protein (ab50037)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

Description

  • Product name

    Recombinant human IL-28A protein
    See all IL-28A proteins and peptides

  • Biological activity

    Biological activity of ab50037 is determined by its ability to activate STAT phosphorylation in an ISRE Luciferase Reporter Assay using human colon carcinoma COLO205 cells.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50037 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • Cytokine ZCYTO20
        • IFN-lambda-2
        • IFNL2
        • IL-28A
        • IL28A
        • IL28A_HUMAN
        • Interferon lambda 2
        • Interferon lambda-2
        • Interleukin 28A
        • interleukin 28A (interferon, lambda 2)
        • Interleukin-28A
        • ZCYTO20
        see all

      • Function

        Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

      • Sequence similarities

        Belongs to the IL-28/IL-29 family.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab50037? Please let us know so that we can cite the reference in this datasheet.

    ab50037 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • Cytokine ZCYTO20
      • IFN-lambda-2
      • IFNL2
      • IL-28A
      • IL28A
      • IL28A_HUMAN
      • Interferon lambda 2
      • Interferon lambda-2
      • Interleukin 28A
      • interleukin 28A (interferon, lambda 2)
      • Interleukin-28A
      • ZCYTO20
      see all

    • Function

      Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

    • Sequence similarities

      Belongs to the IL-28/IL-29 family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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