Recombinant Human IL-17F protein (ab268663)
Key features and details
- Expression system: Escherichia coli
- Purity: >= 95% SDS-PAGE
- Endotoxin level:
- Suitable for: SDS-PAGE
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Product name
Recombinant Human IL-17F protein
See all IL-17F proteins and peptides -
Purity
>= 95 % SDS-PAGE. -
Endotoxin level
Expression system
Escherichia coliAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Additional sequence information
Mature chain.
Specifications
Our Abpromise guarantee covers the use of ab268663 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 3.0
Constituent: 0.29% Sodium citrate
Buffer lyophilized from -
ReconstitutionReconstitute in sterile 4mM HCl at 25 µg/ml containing at least 0.1% HSA or BSA.
General Info
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Alternative names
- CANDF6
- Cytokine ML 1
- Cytokine ML-1
see all -
Function
Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation. -
Tissue specificity
Expressed in activated, but not resting, CD4+ T-cells and activated monocytes. -
Involvement in disease
Candidiasis, familial, 6 -
Sequence similarities
Belongs to the IL-17 family. -
Cellular localization
Secreted. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human IL-17F protein (ab268663)
ab268663 resolved on a 15% SDS-PAGE gel under reducing conditions.
Stained with coomassie blue.
MW ~15.2 kDa.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab268663 has not yet been referenced specifically in any publications.
Preparation and Storage
- CANDF6
- Cytokine ML 1
- Cytokine ML-1
Images
-
SDS-PAGE - Recombinant Human IL-17F protein (ab268663)
ab268663 resolved on a 15% SDS-PAGE gel under reducing conditions.
Stained with coomassie blue.
MW ~15.2 kDa.