Antibodies, Proteins, Kits and Reagents for Life Science

197 673 ₸ Product size

25 µg 197 673 ₸

Order now and get it on Thursday February 25, 2021

Recombinant human IGFBP1 protein (ab50216)

Key features and details

Expression system: Escherichia coli
Endotoxin level:
Active: Yes
Suitable for: WB, SDS-PAGE, Functional Studies

Alternative names
- AFBP
- Alpha pregnancy associated endometrial globulin
- Amniotic fluid binding protein
- Binding protein 25
- Binding protein 26
- Binding protein 28
- Growth hormone independent binding protein
- hIGFBP 1
- hIGFBP1
- IBP 1
- IBP-1
- IBP1
- IBP1_HUMAN
- IGF binding protein 1
- IGF BP25
- IGF-binding protein 1
- IGFBP 1
- IGFBP-1
- IGFBP1
- Insulin like growth factor binding protein 1
- Insulin-like growth factor-binding protein 1
- Placental protein 12
- PP 12
- PP12
see all
Function

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
Sequence similarities

Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.
Post-translational
modifications

Phosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs.
Cellular localization

Secreted.
Target information above from: UniProt accession P08833 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

Western blot - Recombinant human IGFBP1 protein (ab50216)

Anti-IGFBP1 antibody [33627.11] (ab94985) at 1 µg/ml + Recombinant human IGFBP1 protein (ab50216) at 0.1 µg

Secondary
Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution

Developed using the ECL technique.

Performed under reducing conditions.

Exposure time: 30 seconds

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