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Signal Transduction Growth Factors/Hormones TGF

Recombinant Human GDF8 / Myostatin protein (ab269214)

Recombinant Human GDF8 / Myostatin protein (ab269214)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human GDF8 / Myostatin protein
    See all GDF8 / Myostatin proteins and peptides
  • Purity

    >95% by SDS-PAGE .

  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    O14793
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
    • Predicted molecular weight

      43 kDa
    • Amino acids

      24 to 266
    • Additional sequence information

      Propeptide
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab269214 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..

        Constituent: 0.1% Trifluoroacetic acid

        Lyophilized from

      • Reconstitution
        Sterile 20 mM HCl at 0.1 mg/mL

      General Info

      • Alternative names

        • GDF 8
        • GDF-8
        • GDF8
        • GDF8_HUMAN
        • Growth differentiation factor 8
        • Growth/differentiation factor 8
        • MSLHP
        • MSTN
        • Myostatin
        • OTTHUMP00000163498
        see all
      • Function

        Acts specifically as a negative regulator of skeletal muscle growth.
      • Sequence similarities

        Belongs to the TGF-beta family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession O14793 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human GDF8 / Myostatin protein (ab269214)
      SDS-PAGE - Recombinant Human GDF8 / Myostatin protein (ab269214)
      SDS-PAGE analysis of ab269214 at 1ug/lane under (-) non-reducing and (+) reducing conditions. 4-20% Tris glycine gel. Stained with coomassie blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab269214? Please let us know so that we can cite the reference in this datasheet.

    ab269214 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • GDF 8
      • GDF-8
      • GDF8
      • GDF8_HUMAN
      • Growth differentiation factor 8
      • Growth/differentiation factor 8
      • MSLHP
      • MSTN
      • Myostatin
      • OTTHUMP00000163498
      see all
    • Function

      Acts specifically as a negative regulator of skeletal muscle growth.
    • Sequence similarities

      Belongs to the TGF-beta family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession O14793 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human GDF8 / Myostatin protein (ab269214)
      SDS-PAGE - Recombinant Human GDF8 / Myostatin protein (ab269214)
      SDS-PAGE analysis of ab269214 at 1ug/lane under (-) non-reducing and (+) reducing conditions. 4-20% Tris glycine gel. Stained with coomassie blue.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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