Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human GDF6 protein (ab50230)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: WB, Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant Human GDF6 protein
    See all GDF6 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR

    • Specifications

    Our Abpromise guarantee covers the use of ab50230 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    • Reconstitution
      Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

    General Info

    • Alternative names

      • bmp 13
      • bmp13
      • Cartilage Derived Morphogenetic Protein 2
      • cdmp 2
      • CDMP2
      • gdf 6
      • GDF16
      • Growth differentiation factor 6
      • Growth/differentiation factor 16
      • Growth/differentiation factor 6
      • KFM
      • KFS
      • KFS1
      • KFSL
      • Klip Feil malformation
      • Klippel Feil malformation
      • Klippel Feil syndrome
      • LCA17
      • MCOP4
      • MCOPCB6
      • SCDO4
      • SGM1
      see all

    • Relevance

      GDF6 (Growth/differentiation factor 6) is expressed in hypertrophic chondrocytes during embryonic development of long bones and is required for normal formation of bones and joints in the limbs, skull, and axial skeleton. It plays a key role in establishing boundaries between skeletal elements during development. The functional form of GDF6 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains obtained by proteolytic processing of a biologically inactive precursor protein.

    • Cellular localization

      Secreted

Images

  • Western blot - Recombinant Human GDF6 protein (ab50230)
    Western blot - Recombinant Human GDF6 protein (ab50230)
    ab50230 is a homodimer consisting of two 120aa monomers. The homodimer format is expected to run at 27kDa, so the observed band is thought to be the monomer form.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab50230? Please let us know so that we can cite the reference in this datasheet.

ab50230 has not yet been referenced specifically in any publications.

Preparation and Storage

  • bmp 13
  • bmp13
  • Cartilage Derived Morphogenetic Protein 2

Images

  • Western blot - Recombinant Human GDF6 protein (ab50230)
    Western blot - Recombinant Human GDF6 protein (ab50230)
    ab50230 is a homodimer consisting of two 120aa monomers. The homodimer format is expected to run at 27kDa, so the observed band is thought to be the monomer form.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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