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Signal Transduction Growth Factors/Hormones FGF

Recombinant human FGF17 protein (ab9991)

Recombinant human FGF17 protein (ab9991)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant human FGF17 protein
    See all FGF17 proteins and peptides
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      25 kDa
  • Associated products

    • Related Products

      • Anti-FGF17 antibody (ab9990)

    Specifications

    Our Abpromise guarantee covers the use of ab9991 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized
    • Additional notes

      The ED50, as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors, is 1 x 106 units/mg.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituents: 0.164% Sodium phosphate, 0.29% Sodium chloride

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      For lot specific reconstitution information please contact our Scientific Support Team.

    General Info

    • Alternative names

      • FGF 13
      • FGF 17
      • FGF-17
      • FGF13
      • Fgf17
      • FGF17_HUMAN
      • Fibroblast growth factor 17
      • HH20
      see all
    • Function

      Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
    • Tissue specificity

      Preferentially expressed in the embryonic brain.
    • Sequence similarities

      Belongs to the heparin-binding growth factors family.
    • Developmental stage

      Detected in embryos at E14.5, but not at E10.5 and E19.5. Preferentially expressed in the neuroepithelia of the isthmus and septum of the embryonic brain at E14.5.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession O60258 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • Sandwich ELISA - Recombinant human FGF17 protein (ab9991)
    Sandwich ELISA - Recombinant human FGF17 protein (ab9991)
    Standard curve for FGF11 (Analyte: ab9991); dilution range 1pg/ml to 1µg/ml using Capture Antibody ab89270 at 1µg/ml and Detector Antibody ab9990 at 0.5µg/ml.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab9991? Please let us know so that we can cite the reference in this datasheet.

    ab9991 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituents: 0.164% Sodium phosphate, 0.29% Sodium chloride

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      For lot specific reconstitution information please contact our Scientific Support Team.

    Images

    • Sandwich ELISA - Recombinant human FGF17 protein (ab9991)
      Sandwich ELISA - Recombinant human FGF17 protein (ab9991)
      Standard curve for FGF11 (Analyte: ab9991); dilution range 1pg/ml to 1µg/ml using Capture Antibody ab89270 at 1µg/ml and Detector Antibody ab9990 at 0.5µg/ml.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Alternative products to Recombinant human FGF17 protein (ab9991)

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    • Recombinant Mouse FGF17 protein (His tag) (ab215628)

      Applications: SDS-PAGE

    •  
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      Recombinant Human FGF17 protein (denatured) (ab156316)

      Applications: SDS-PAGE

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