Recombinant human FGF1 protein (Active) (ab268551)
Key features and details
- Expression system: Escherichia coli
- Purity: >= 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Preparation and Storage
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Alternative names
- Acidic fibroblast growth factor
- aFGF
- Beta endothelial cell growth factor
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Function
The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. -
Sequence similarities
Belongs to the heparin-binding growth factors family. -
Cellular localization
Secreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1. - Information by UniProt
Images
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Functional Studies - Recombinant human FGF1 protein (Active) (ab268551)
The ED50 of ab268551 was determined by the dose-dependent stimulation of mouse fibroblasts and it was
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SDS-PAGE - Recombinant human FGF1 protein (Active) (ab268551)ab268551 resolved on a 15% SDS-PAGE under reducing conditions.
Stained with coomassie blue.
MW ~16 kDa.