Recombinant Human FCN3 protein (ab160086)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
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Product name
Recombinant Human FCN3 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAP GSPGEKGAPGPQGPPGPPGKMGPKGEPGPRNCRELLSQGATLSGWYHLCL PEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEF WLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLAL GKFSEGTAGDSLSLHSGRPLTTYDADHDSSNSNCAVIVHGAWWYASCYRS NLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR -
Amino acids
1 to 288 -
Tags
GST tag N-Terminus
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Preparation and Storage
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Alternative names
- Collagen/fibrinogen domain containing lectin 3 p35
- Collagen/fibrinogen domain containing protein 3
- FCN 3
see all -
Relevance
FCN3 (Ficolin 3) is involved in the serum exerting lectin activity. In human serum, there are two types of ficolins, both of which have lectin activity. FCN3 is a thermolabile beta 2 macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. It can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. -
Cellular localization
Secreted. Note: Found in blood plasma, bronchus, alveolus and bile duct.
Images
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SDS-PAGE - Recombinant Human FCN3 protein (ab160086)ab160086 on a 12.5% SDS-PAGE stained with Coomassie Blue.