Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human DNER protein (ab108954)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: DDDDK tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human DNER protein
    See all DNER proteins and peptides

  • Purity

    > 90 % SDS-PAGE.
    ab108954 is 0.2µm filtered.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q8NFT8

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      100 kDa including tags

    • Amino acids

      1 to 640

    • Tags

      DDDDK tag C-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab108954 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

      Constituent: PBS

    General Info

    • Alternative names

      • bet
      • Brain EGF repeat-containing transmembrane protein
      • Bret
      • Delta and Notch-like epidermal growth factor-related receptor
      • Delta notch like EGF repeat containing transmembrane
      • Delta/notch like EGF repeat containing
      • Delta/notch-like EGF-related receptor
      • Dner
      • DNER_HUMAN
      • PRO299
      • Transmembrane protein Bet
      • UNQ26
      see all

    • Function

      Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

    • Tissue specificity

      Expressed in brain, spinal cord and adrenal gland.

    • Sequence similarities

      Contains 10 EGF-like domains.
      Contains 1 follistatin-like domain.

    • Cellular localization

      Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab108954? Please let us know so that we can cite the reference in this datasheet.

ab108954 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Constituent: PBS

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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