Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CXCL17/DMC protein (Active) (ab243127)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, HPLC, SDS-PAGE

Description

  • Product name

    Recombinant human CXCL17/DMC protein (Active)
    See all CXCL17/DMC proteins and peptides

  • Biological activity

    Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0 μg/ml, corresponding to a specific activity of >200 IU/mg.

  • Purity

    > 98 % SDS-PAGE.
    Purity >96% as determined by SDS-PAGE and HPLC.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q6UXB2

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      SSLNPGVARGHRDRGQASRRWLQEGGQECECKDWFLRAPRRKFMTVSGLP KKQCPCDHFKGNVKKTRHQRHHRKPNKHSRACQQFLKQCQLRSFALPL

    • Predicted molecular weight

      12 kDa

    • Amino acids

      22 to 119

    • Additional sequence information

      Full-length mature chain lacking the signal peptide.

    • Specifications

    Our Abpromise guarantee covers the use of ab243127 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      HPLC

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

       This product was previously labelled as CXCL17

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituent: PBS

      0.2 µm filtered

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Briefly centrifuge prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20 °C or below. Further dilutions should be made in appropriate buffered solutions.

    General Info

    • Alternative names

      • 13.6 kDa protein
      • C-X-C motif chemokine 17
      • chemokine (C-X-C motif) ligand 17
      • CXCL17
      • Dcip1
      • Dendritic cell and monocyte chemokine-like protein
      • DMC
      • UNQ473
      • UNQ473/PRO842
      • VCC1
      • VEGF co-regulated chemokine 1
      see all

    • Relevance

      Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections.

    • Cellular localization

      Secreted.

Images

  • SDS-PAGE - Recombinant human CXCL17/DMC protein (Active) (ab243127)
    SDS-PAGE - Recombinant human CXCL17/DMC protein (Active) (ab243127)
    SDS Page analysis of ab243127

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab243127? Please let us know so that we can cite the reference in this datasheet.

ab243127 has not yet been referenced specifically in any publications.

Preparation and Storage

  • 13.6 kDa protein
  • C-X-C motif chemokine 17
  • chemokine (C-X-C motif) ligand 17

Images

  • SDS-PAGE - Recombinant human CXCL17/DMC protein (Active) (ab243127)
    SDS-PAGE - Recombinant human CXCL17/DMC protein (Active) (ab243127)
    SDS Page analysis of ab243127

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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