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Microbiology Organism Virus RNA Virus ssRNA positive strand virus SARS Coronavirus

Recombinant human coronavirus SARS-CoV-2 Spike RBD (mutated N501Y) protein (Active) (ab281469)

Recombinant human coronavirus SARS-CoV-2 Spike RBD (mutated N501Y) protein (Active) (ab281469)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: CHO cells
  • Purity: > 70% SDS-PAGE
  • Active: Yes
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, Functional Studies

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Description

  • Product name

    Recombinant human coronavirus SARS-CoV-2 Spike RBD (mutated N501Y) protein (Active)
    See all SARS-CoV-2 Spike RBD proteins and peptides
  • Biological activity

    ab281469 binds to immobilized recombinant human ACE-2 (19-740) protein.

  • Purity

    > 70 % SDS-PAGE.

  • Expression system

    CHO cells
  • Accession

    P0DTC2
  • Protein length

    Protein fragment
  • Animal free

    Yes
  • Nature

    Recombinant
    • Species

      Human coronavirus
    • Sequence

      RVQPTESIVR FPNITNLCPF GEVFNATRFA SVYAWNRKRI SNCVADYSVL YNSASFSTFK CYGVSPTKLN DLCFTNVYAD SFVIRGDEVR QIAPGQTGKI ADYNYKLPDD FTGCVIAWNS NNLDSKVGGN YNYLYRLFRK SNLKPFERDI STEIYQAGST PCNGVEGFNC YFPLQSYGFQ PTYGVGYQPY RVVVLSFELL HAPATVCGPK KSTNLVKNKC VNF
    • Predicted molecular weight

      39 kDa including tags
    • Amino acids

      319 to 541
    • Modifications

      mutated N501Y
    • Tags

      His tag C-Terminus
    • Additional sequence information

      GenBank: MN908947.3. Wuhan-Hu-1 isolate.

Images

  • Functional Studies - Recombinant human coronavirus SARS-CoV-2 Spike RBD (mutated N501Y) protein (Active) (ab281469)
    Functional Studies - Recombinant human coronavirus SARS-CoV-2 Spike RBD (mutated N501Y) protein (Active) (ab281469)

    Functional analysis of ab281469.

    Binding activity measured in a functional ELISA. Compared to the wild-type protein (ab273065), ab281469 exbits increased binding potency for immobilized recombinant human ACE-2 (19-740).

  • SDS-PAGE - Recombinant human coronavirus SARS-CoV-2 Spike RBD (mutated N501Y) protein (Active) (ab281469)
    SDS-PAGE - Recombinant human coronavirus SARS-CoV-2 Spike RBD (mutated N501Y) protein (Active) (ab281469)

    SDS-PAGE analysis of ab281469.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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